Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Set_01_ATM_minus_versus_SCID.phenotype_ATM_minus_versus_SCID.cls #ATM_minus_versus_SCID |
| Phenotype | phenotype_ATM_minus_versus_SCID.cls#ATM_minus_versus_SCID |
| Upregulated in class | SCID |
| GeneSet | BIOCARTA_CASPASE CASCADE IN APOPTOSIS |
| Enrichment Score (ES) | -0.66753954 |
| Normalized Enrichment Score (NES) | -1.9036069 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.11616539 |
| FWER p-Value | 0.222 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | LMNA | 1421654_a_at 1425472_a_at 1426868_x_at 1452212_at 1457670_s_at | 3954 | 0.827 | -0.1406 | No | ||
| 2 | APAF1 | 1450223_at | 6539 | 0.437 | -0.2374 | No | ||
| 3 | PRF1 | 1451862_a_at | 6879 | 0.400 | -0.2337 | No | ||
| 4 | CASP4 | 1449591_at | 7991 | 0.288 | -0.2705 | No | ||
| 5 | GZMB | 1419060_at | 10282 | 0.079 | -0.3712 | No | ||
| 6 | CASP1 | 1449265_at | 10900 | 0.028 | -0.3980 | No | ||
| 7 | BIRC2 | 1418854_at | 11288 | -0.008 | -0.4153 | No | ||
| 8 | PARP1 | 1422502_at 1422503_s_at 1435368_a_at 1443573_at | 11562 | -0.034 | -0.4261 | No | ||
| 9 | BIRC3 | 1421392_a_at 1425223_at | 12726 | -0.137 | -0.4726 | No | ||
| 10 | DFFB | 1421229_at 1437051_at | 15174 | -0.382 | -0.5658 | No | ||
| 11 | LMNB1 | 1423520_at 1423521_at | 15294 | -0.394 | -0.5523 | No | ||
| 12 | CASP8 | 1424552_at | 16947 | -0.612 | -0.5982 | No | ||
| 13 | LMNB2 | 1451849_a_at | 18468 | -0.911 | -0.6237 | Yes | ||
| 14 | SREBF1 | 1426690_a_at | 19353 | -1.096 | -0.6112 | Yes | ||
| 15 | CASP3 | 1426165_a_at 1430192_at 1449839_at | 19993 | -1.310 | -0.5773 | Yes | ||
| 16 | ARHGDIB | 1426454_at | 20525 | -1.576 | -0.5256 | Yes | ||
| 17 | CASP6 | 1415995_at 1458715_at | 20811 | -1.766 | -0.4536 | Yes | ||
| 18 | CASP9 | 1426125_a_at 1437537_at 1457816_at | 20906 | -1.849 | -0.3689 | Yes | ||
| 19 | DFFA | 1450885_at 1457564_at | 21032 | -1.942 | -0.2811 | Yes | ||
| 20 | CASP2 | 1448165_at | 21150 | -2.026 | -0.1888 | Yes | ||
| 21 | CASP7 | 1426062_a_at 1448659_at | 21858 | -4.665 | 0.0036 | Yes |
